الفهرس | Only 14 pages are availabe for public view |
Abstract The aim of our work was detection of bacterial biofilm formation,antibiotic senstivity and presence of fungal isolates in cases of chronic suppurative otitis media. In our study,Pseudomonas Aeurginosa was the most common bacteria found(37.5%) followed be Klebsiella Spp(10%) and staph.aeureus (7.5%). Our results of Antibiotic sensitivity were variable and this gave us an idea about importance of culture and sensitivity . Psedomonas was sensitive to Ciprofloxacin(Cip)(73.3%), IPM(Impineam) 73.3%,Meronem(MEM)(73.3%) followed by AK(Amikacin)(66.7%) and TZP(piperacillin+Tazobactam)(60%) Staph.aureus was 100% sensitive to CN(Garamicin) ,AK(Amikacin) ,VA(Vancomyxin) ,TEC(Tecoplamin) and LZD(Linezolid) followed by 67.7% to FD(Fucidin), DO(Doxycyclin) and CTX(Cefotaxime). Klebseilla.spp was 100 % sensitive to OFX(Floxacin),TZP(Tazocin), CN(Garamycin),TOB(Tobramycin),FOX(Cefoxitin)IPM(Imipenem), Cip(Ciprofloxacin),LEV(Levofloxacin),AK(Amikacin),SCF(Sulperazone),TGC(Tigecycline) and MEM(Meronem). We noticed that fungal infection ocuured without clinical evidence of this infection,Candida infection in 6 out of 40 cases(15%) and Aspeigillus was 4 out of 40 cases(10%) thus fungal infection occurred in 25% 134 Mixed bacterial and fungal infections occurred in 10% and mixed fungal infection occur in 2.5%. Pseudomonas was the most frequent Biofilm forming bacteria that often caused moderate biofilm formation(53.3%) We found also that pseudomonas resisting antibiotics 2 cases out of 40(5%) and staph.aureus I case (2.5%) and by searching biofilm of those,they were either moderate or ston f biofilm forming thus we can link antibiotic resistance to biofilm. |