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Abstract The term medical thoracoscopy can be used to describe the diagnostic and therapeutic exploration of the pleural space carried out by the pulmonary physician, in the endoscopy unit, mostly under local anesthesia with or without conscious sedation. With thoracoscopy, one can visualize the entire visceral and parietal pleura and take pleural biopsy from suspicious sites under vision. Forceps biopsy is the commonest used instrument to obtain thoracoscopic specimens from suspected pleural lesions; however this procedures may be associated with bleeding that hinder further biopsy, additionally the decision to take biopsy could be difficult specially when the targeted lesions are on the visceral pleura or near vascular structure. On the other hand pleural brush could be used to obtain pleural specimens through the medical thoracoscopy from suspected areas either in parietal, visceral pleura or near vascular structure safely. The use of pleural lavage at the time of thoracoscopy would provide a higher diagnostic yield than the cytologic analysis of the fluid obtained at thoracentesis and could provide additional diagnostic information to the thoracoscopic biopsy. |