الفهرس 
Introduction and aim of the workOnly 14 pages are availabe for public view
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Abstract
Metabolic syndrome is characterized by a combination of various risk factors that imply additional cardiovascular morbidity that is greater than the sum of the risks associated with each individual component. Patients with arthropathy are at increased risk of mortality and cardiovascular events is the leading cause of death among such patients.
Among the various types of arthropathy; osteoarthritis, gout and immunoinflammatory diseases have been associated with an increase in the prevalence of metabolic syndrome and cardiovascular diseases. Studies have demonstrated that atherosclerosis is accelerated in patients with arthropathic diseases, although the causal factors have not yet to be completely elucidated.
There are few studies evaluating metabolic syndrome association with arthropathy. The prevalence was found to range from 16% to 62%. We conducted the current study to characterize the prevalence and features of arthropathy in patients with metabolic syndrome. 30 patients (Group I) suffering from metabolic syndrome associated arthropathy were included in the current study and according to the types of arthropathy in those patients they were classified into 3 subgroups: Subgroup (A): included 16 patients suffering from Osteoarthritis, Subgroup (B): included 11 patients suffering from gouty arthritis and Subgroup (C): included 3 patients suffering from rheumatoid arthritis. Also, 20 healthy subjects (Group II) were selected to serve as control group.
All the patients included in this study were subjected to the following:
1. History taking and clinical examination including: weight, hight, waist circumference, body mass index (BMI) and blood pressure measurement.
2. Locomotor examination including full knee examination.
3. Assessment of arthropathy
4. Laboratory investigations including: fasting blood sugar, triglycerides, HDL and CRP.
5. Plain radiographs of the joints affected (A/P, lateral & skyline views).
Mean levels of FBS, TGS, and waist circumference were significantly higher in patients with MS as compared with subjects without MS. The hypertensive and CRP positive cases were also significantly more frequent in the group of arthropathy patients with MS as compared without MS. HDL level showed no significant difference between both groups.
Clinically, patients with arthropathy and MS were significantly more frequently affected than subjects without MS.
FBS, TGS, waist circumference levels and percentage of patients with hypertension were significantly higher in patients with arthropathy associated metabolic syndrome than without metabolic syndrome while HDL showed no significant difference between patients with and without MS.