الفهرس 
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Abstract
The present study was carried on 80 full term neonates with age ranged from 1-7 days who were grouped into 2 groups (Study group) included 60 full term neonates with HIE and then subdivided according to degree of hypoxia into three groups: mild, moderate and severe hypoxia and (Control group) included 20 apparently healthy full term neonates who were selected from outpatient neonatal clinic.
All studied groups were subjected to full medical history, clinical examination and laboratory investigations including: complete blood count (CBC), early arterial blood gases (ABG), renal function tests, liver function tests, serum electrolytes and measurement of serum Selenium level. Apgar score was done at1 minute and 5minutes after delivery for all studied neonates.
In our study we reported that there was no effect of neonatal age, gestational age, birth weight, sex and mode of delivery on serum Selenium level in studied groups.
Also, our study revealed that according to laboratory data finding there was a high levels of urea, creatinine, SGOT, SGPT, K and low levels of PH, Hb, Ca, Na, platelets and WBCs count in neonates with HIE.
Moreover there were significant differences as regarding Hb level, platelets count, base deficit, urea, creatinine, SGOT, SGPT, Na, K and Ca levels but in-significant difference as regarding WBCs count.
A significant positive correlation between serum selenium level and Hb, calcium levels and platelets count, but a non-significant positive correlation with K, creatinine levels.
Also a significant negative correlation with base deficit, SGOT and SGPT levels were present, but a non-significant negative correlation with WBCs count, PH, urea, Na levels.
Moreover in our study we found that Apgar score which was done at1 minute and 5minutes after delivery was less in patients than controls and there was high statistical significant difference between two groups and significant positive correlation between serum selenium level and Apgar score in study group.
Furthermore, we found that serum selenium level is significantly lower in neonates with HIE than controls; also serum selenium level had significant negative correlation with the degree of hypoxia.
Our study adds the following novel information:
(1) Serum Selenium level in hypoxic neonates is lower than healthy neonates.
(2) Serum Selenium level is inversely correlated with the degree of hypoxia.
(3) High correlation between serum selenium level and results of Apgar score in neonates.