الفهرس 
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Abstract
Polycystic ovary syndrome is an endocrine and metabolic heterogeneous disorder, with a likely genetic origin, influenced by environmental factors such as nutrition and physical activity. The main clinical features of PCOs are related to hyperandrogenism, such as hirsutism, acne and menstrual disorders. PCOs is also associated with overweight or obesity, mainly abdominal adiposity. The etiology of PCOs is unknown. The genetic origin is based on the observation that PCOs is more frequent among the sisters and mothers of these patients (Moran et al., 2012). The aim of the present study is to assess the pregnancy outcomes of the pregnant women with polycystic ovary syndrome. The study was conducted in the labor ward of Obstetrics and Gynecology department, Qena University and Qena General Hospital. Total number of 720 women was included in the study after receiving their written consents for participation (600 women in the non PCOs group and 120 women in the PCOs group). Tools of data collection was a semi structured interview questionnaire which was designed by the researcher after reviewing the literature and researches which were relevant to the present study. This questionnaire consisted of different groups of questions to assess pregnancy outcomes in the women who are pregnant normally in comparison to women who have a history of PCOs. The main findings of this study were:
1-Near half of the studied women in the non PCOs group (43.7 %) and more than one third (39.2 %) in the PCOs group were in the age group of less than 25 years and their mean age were (26.3 + 5.2) and (26.9 + 5) respectively with no statistical difference among both groups (p = 0.587).
2-Most of the women in both groups were with secondary education, (45 %) in the PCOs group Vs (41.5 %) in the non PCOs group, the great majority of them were housewives (96.7 %) and (96.8 %) respectively and most of them were from rural area (75.8 %) and (74.8 %) respectively with no statistical difference among both groups (p = 0.436).
3-Family history of PCOs represents (30.8 %) in the PCOs group and irregular menstruation represents (45 %) Vs (6.8 %) and (7.2 %) in the non PCOs group respectively with highly statistical significant relationship (p = 0.001).
4-In relation to history of infertility in the PCOs group the present study showed that nearly two thirds (64.2 %) were infertile for less than 5 years, one quarter (25 %) were infertile for 5 to less than 10 years, about (50 %) had hirsutism and most of them (86.7 %) conceived by ovulation induction.
5-Regarding to the current pregnancy condition among both groups, the present study showed that (21.7 %) of the PCOs group had normal pregnancy and half of them (50 %) had normal labor while most of them (79.2 %) delivered by CS Vs (75.7 %), (79.8 %) and (53.8 %) in the non PCOs respectively with highly statistical significant relationship (p = 0.001).
6-The present study showed that, the neonatal outcomes in the PCOs group represents (19.2 %) of the babies had APGAR score of less than 7 at the first minute, (20.8 %) had respiratory distress, (9.2%) were macrosomic, (9.2 %) were LBW and (20.8 %) were admitted to the NICU Vs (2.2 %), (6.2 %), (4.2 %), (3.8 %) and (4.3 %) respectively in the non PCOs group with highly statistical significant relationship between both groups (p = 0.001), (p = 0.001), (p = 0.039), (p = 0.027) and (p = 0.001) respectively.
7-The present study revealed that there is a statistical significant relationship in the current pregnancy condition among age groups in the non PCOs group. Normal pregnancy represents (21 %) in the age group of less than 30 years and (23.5 %) in the age group of 30 years or more in the PCOs group Vs (76 %) and (74.7 %) in the non PCOs group respectively with a highly statistical significant relationship among both groups (p = 0.027).
8-Also the present study revealed that there is highly statistical significant relationship in the type of complications of labor in the age groups among both groups. Preterm represented (5.8 %) and macrosomia represented (11.6 %) in the age group of less than 30 years in the PCOs group Vs (3 %) and (3 %) respectively in the age group of 30 years or more while in the non PCOs group they represented (2.3 %) and (3 %) in the age group of less than 30 years Vs (0 %) and (3.6 %) in the age group of 30 years or more respectively with a highly statistical significant relationship among both groups (p = 0.018) and (p = 0.016) respectively.
9-Also the present study showed that there is no statistical significant difference between the methods of conceiving and the current pregnancy condition (p = 0.082). Complicated pregnancy represents (100 %) in the spontaneous pregnancy group and (76.4 %) in the ovulation induction and LOD group. Also the study revealed that CS represented (81.8 %) in the PCOs group Vs (50 %) in the PCOs group respectively with highly statistical significant relationship between both groups (p = 0.001).
10-The study also showed that there is high statistical significant relationship between obesity and the type of complications between both groups. In the PCOs group hypertension represents (0 %) in less than 20 group, (7.1 %) in 20 to less than 25 group, (17.9 %) in 25 to less than 30 group and (18.8 %) in 30 or more group Vs (0 %), (0.7 %), (1.3 %) and (0 %) respectively in the non PCOs group with highly statistical significant relationship (p = 0.053). Also DM represents (0 %), (7.1 %), (21.4 %) and (8.3 %) Vs (0 %), (0.9 %), (0 %) and (0 %) respectively in the non PCOs group with highly statistical significant relationship between both groups (p = 0.024).
11-Also the study showed that there is highly statistical significant relationship between obesity and the mode of delivery between both groups (p < 0.001). In the PCOs group CS represents (0%) in less than 20, (66.7 %) in 20 to less than 25, (85.7 %) in 25 to less than 30 and (89.6 %) 30 or more group Vs (52.4 %), (51.3 %), (55.3 %) and (85.3 %) in the non PCOs group respectively. In conclusion, women with PCOs are more likely to have menstrual irregularity, hyperandrogenism, nulliparous, had increased BMI, higher rates of ovulation induction, had higher rates of complications during their pregnancy such as early miscarriage, PIH, DM, PET, high multiple pregnancy rate and also they had complications during labor such as preterm labor, post term and CS. Also their babies had a higher rate of APGAR score of less than 7, respiratory distress, LBW, macrosomia and admission to NICU than the non PCOs group. It is recommended that the pregnant mother with a previous history of PCOs should be followed up regularly to avoid or to detect early the complications that arise with the presence of PCOs. Obese women should reduce their weight through life style modification as diet and exercise. Also mothers with a previous history of PIH, DM, PET or macrosomic baby during their previous pregnancy should be screened regularly.