الفهرس 
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Abstract
Background: End-stage renal disease (ESRD) is a worldwide public health problem with an increasing incidence, prevalence, poor outcomes, and high cost. Many patients with ESRD who are undergoing chronic hemodialysis treatment suffer from sleeping disturbance. The aim of this study was to assess factors affecting sleep disturbance and quality of life in patients undergoing hemodialysis. The study design was a descriptive survey design. It was conducted in hemodialysis unit in urology and nephrology center at Mansoura University Hospital. The study sample was a convenience sample of 100 adult patients from both sex , age ranged 18-60 years old, and undergoing maintenance hemodialysis program. Patients’ assessment was done through using the following data collection tools: 1) Sociodemographic characteristics and Patient Health Status, 2) The Pittsburgh Sleeping Quality Index (PQSI). 3) Quality of Life Index (The Karnofsky Performance Scale and Quality of Life Index (Dialysis Version (QLI) The results of this study showed that there are many factors causing sleep disturbance that affect quality of life among hemodialysis patients, and Significant positive relation between quality of sleeping and quality of life (r=, 644 & p < 0.05). This study concluded that majority of patients undergoing hemodialysis (HD) program had sleeping disturbance that affect negatively on quality of life and functional performance ability. This study recommends 1) Comprehensive simple Arabic booklet that includes instructions to improve sleep quality and how avoid sleep disturbance to be handled to all patients on hemodialysis treatment program. 2) Developing an educational program for nurses about how to avoid sleeping disturbances and improving quality of sleep. 3) Encourage nurses to apply complementary and alternative medicine (CAM) to improve sleeping disturbances among HD patients 4) Further researches to different geographical areas and large sample to assess types of sleeping disturbance, incidence, intensity, associated factors, therapeutic management, and to investigate treatment success to improve objective and subjective parameters of sleeping disorders for hemodialysis patients. Apply intervention that improves sleep quality in these patients.