الفهرس 
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Abstract
our study included 100 patients diagnosed with acute ischemic stroke admitted to Neurology Department, Sohag University Hospital .
We think, our study group reflects the population of upper Egypt because of the variability of the patients attending to our hospital from the various parts of upper Egypt.
Our results show the association of some inflammatory biomarkers with stroke severity and dependence on discharge suggesting the contribution of inflammation as a prognostic indicator for the development of clinical complications following cerebral acute events.
Actually, there is a substantial interest in the use of biomarkers panel to identify subjects at higher risk for the development of complications following thrombolysis therapy.
The present study examines the association between biomarkers, paying attention, in particular, to the hypothesis that different plasma levels of biomarkers assessed at baseline in subjects affected by AIS could be predictive for developement of both size lesions and clinical outcome.
These results further confirm our assumption that multivariate analyses of relevant biomarkers are necessary to reduce the risk of inaccurate prognosis.
Finally we conclude that higher levels of WBCS and APTT in our study were significantly associated with poor stroke outcome ,in contrast to higher levels of serum triglycerides ,uric acid and Albumin which were associated with better stroke outcome .
There was no significant assosiation between INR , ESR and platelets count and stroke outcome ,also non of the above mentioned biomarkers was significantly correlated with stroke volume .
Lastly , the following recommendations must be put in mind :
- More studies should be done to determine the relationship between other inflammatory markers and acute ischemic stroke outcome .
-Further understanding of the relationship between other inflammatory markers and acute ischemic stroke outcome must be evaluated and investigated in more and larger studies.
-Another study to evaluate the prognosis and long term follow up for patients with acute ischemic stroke and relation to inflammatory blood biomarker.
- Increase the number of informative markers and to assess their relative contributions to diagnosis, prediction of stroke severity and outcome, and stratification of patients for stroke therapy in a practical and cost-effective manner.
- further studies which correlate previously mentioned blood biomarkers with stroke volume should be done using magnetic resonance imaging, instead of CT scan.