الفهرس 
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Abstract
Pityriasis versicolor is a common, benign, superficial cutaneous fungal infection usually characterized by hypopigmented or hyperpigmented macules and patches on the chest and the back. In patients with a predisposition, tinea versicolor may chronically recur.Tinea versicolor is caused by the dimorphic, lipophilic organisms in the genus Malassezia, formerly known as pitrysporum ovale.
The organism can be found on healthy skin and on skin regions demonstrating cutaneous disease. In patients with clinical disease, the organism is found in both the yeast (spore) stage and the filamentous (hyphal) form.
An antifungal agent is a substance that kills fungi or inhibits its growth. There are many types of antifungal agents used to treat a range of illnesses and conditions caused by fungi. Some of these agents are topical while others are meant to be ingested.Systemic antifungal agents can be generally grouped on the basis of their site of action in pathogenic fungi.
Antifungal resistance continues to grow and evolve and complicate patient management, despite the introduction of new antifungal agents. In vitro susceptibility testing is often used to select agents with likely activity for a given infection, but perhaps its most important use is in identifying agents that will not work, i.e. to detect resistance.
In our study, we investigated 100 individuals with pityriasis versicolour as evident by clinical examination attending dermatology outpatient clinic inBeni-Suef University Hospital, where skin scraping of skin lesion was done and transferred to the microbiology laboratory for examination and in-vitro antifungal susceptibility.
We found that malassezia furfurhad a frequency of 49.3%, malassezia globosa21.7%, malassezia pachydermatis11.6%, malassezia sympodialis10.1 % andmalassezia sloofiae had afrequency of 7.2%.
As regards in-vitro antifungal susceptibility testing, the following antifungal ketoconazole,fluconazole,itraconazole, voriconazole,amorolfine, miconazole, bifonazole, econazole and terbinafine were used to the isolated malassezia strains.