الفهرس 
AcknowledgmentOnly 14 pages are availabe for public view
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Abstract
This study was conducted on 404 patients with chronic hepatitis C virus infection who were randomly selected from the outpatient clinic of Viral Hepatitis Treatment Unite, Beni Suef General Hospital.
This study recommended a pretreatment scoring system for Egyptian patients infected with HCV , as a predictor of sustained viral response (SVR) to pegylated interferon plus ribavirin therapy.
This study instructed 4 pretreatment scoring systems (166 Patients) , as predictors for SVR
Score 1 , contained all variables
Score2” Biopsy + RNA + AFP”
Score3”RNA + AFP”
Score4”AFP alone
Then 3 test groups (with the other 238 Patients) were re-evaluated using these scoring systems
Test G. 1
Score 4 had the highest Sensitivity100.0%, Score 1 had the highest specificity72.2%,
Test G. 2
Score 4 had the highest Sensitivity 88%, Score 2 had the highest specificity 59.62%
Test G. 3
Score 4had the highest Sensitivity 94%, Score 1 had the highest specificity 64%. AFP alone had the highest Sensitivity 100%, 88%, 94%, , in all 3 test groups.
Score 1 of all variables had the highest specificity in two test groups 64%, 72.2%, while score 2 had the highest specificity in one test group(59,6%)
By study of predictors of SVR:
Our study showed that patient‘s age, weight, random blood sugar, ALT level, PC%, total bilirubin level, staging of fibrosis on liver biopsy, and AFP level correlated well with SVR rates.
On the other hand patient‘s gender, viral load (RNA copies), AST level, H/O of schistosomal infection, grading of activity on liver biopsy and platelets count did not correlate with SVR rates.