الفهرس 
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Abstract
Obesity has become an epidemic worldwide condition, especially in the Western world. The pathophysiology of obesity is complex and still poorly understood, but it includes a multifactorial genesis including genetic, behavioral, psychological, and other causes. To date, non-surgical treatments have not been very effective in treating obesity, regardless of the approach used, with rates of recurrence up to 90%. Surgery is currently accepted as the only treatment approach, with the greatest and longest-lasting success in achieving weight loss. Bariatric surgery has gained popularity in the past two decades as an alternative to weight-loss diets.
The history of bariatric surgery can be traced back to the 1950s; it is an extraordinary example of how new therapeutic ideas and new surgical techniques influence the development of a surgical field. Weight-loss operations can be divided into restrictive procedures and malabsorptive procedures. Malabsorptive procedures reduce the absorption of calories, proteins, and other nutrients. In contrast, restrictive bariatric procedures decrease food intake and promote a feeling of fullness (satiety) following meals. Some operations are a combination of both. LSG is an example of purely restrictive procedures, while LMGB is an example of combination of both.
The aim of this study was to compare Laparoscopic Sleeve Gastrectomy (LSG) versus Laparoscopic Mini-Gastric Bypass (LMGB) in management of morbidly obese patients regarding; mean operative time, conversion rate, hospital stay, rate of complications, and amelioration of comorbidities, and weight loss within one year, post-operative quality of life and eating pattern and effect of both surgery on serum GLP-1 six weeks postoperatively.
This study was carried out on forty morbid obese patients in the Gastrointestinal Surgery Unit of Alexandria Main University Hospital. All patients were followed up for 12 months. They were divided by simple randomization method into 2 groups; Group A, managed by Laparoscopic Sleeve Gastrectomy (LSG) and Group B, managed by Laparoscopic Mini-Gastric Bypass (LMGB).
There was no statistically significant difference between both groups regarding preoperative demographic data, obesity related comorbidities and anthropometric measures.