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Abstract Susceptibility-weighted imaging (SWI) is a new technique that exploits the magnetic susceptibility among various tissues, it relies on utilization of a high resolution, three dimensional fully flow compensated gradient echo sequence. This study aimed to assess the role of susceptibility-weighted imaging in diagnosis of cerebral cavernous malformations. This study was conducted on 15 patients with suspected cavernous malformations. It included nine males and six females. Their ages ranged between 10 years and 62 years with a median age of 36 years. All patients were subjected to full history taking, thorough clinical assessment and conventional MRI study of the brain with Susceptibility-weighted imaging. Regarding the site of the lesion, supratentorial lesions were more common and seen in 13 cases while infratentorial lesions seen in seven cases provided that there were cases showed multiple lesions with different locations. Individuals with cavernous malformations in this study presented with seizures which were the most common clinical presentations found in eight cases followed by headache which is seen in five cases. Two cases were completely asymptomatic and diagnosed during routine imaging evaluation. In the current study, 14 cases showed old phase of bleeding while two cases showed active bleeding noticing that there was one case had two different lesions with two different phases of bleeding. Based on Zabramski et al, the lesions were classified into four types according to the MRI findings. The most common type was type II seen in ten cases. There was no contrast enhancement of cavernoma itself in all of the 15 cases but one case showed association with developmental venous anomaly which represented by caput medusa head sign after contrast administration. Regarding the management, surgical removal of the lesions was done in eight cases while conservative treatment was performed in seven cases. The management depends on clinical presentations and the imaging findings which include the site of the lesion(s), multiplicity and the actual phase of bleeding. |