الفهرس 
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Abstract
The aim of this study is to:
1- Investigate the anti-hyperglycemic activity of different extracts of J. curcas leaves and their mechanism compared with the oral antidiabetic drug glibenclamide (daonil) in normal and STZ-induced diabetes in rats.
2- Evaluate the possible antioxidant activity of J. curcas leaves extract.
3- Identify the main constituents presented in J. curcas leaves extract which are responsible for the bioactivity.
The results could be summarized and concluded as follows:
1. Phytochemical compounds of J. curcas leaves:
The qualitative phytochemical screening of J. curcas leaves revealed the presence of the following secondary metabolites flavonoids, tannins, phenolics, saponins, coumarines, sterols and triterpenes. This showed that, the leaves of J. curcas contained different secondary metabolites which had several biological activities.
2. Percentage yield of extraction by different solvents from J. curcas leaves:
The percentage yield of extraction for petroleum ether, ethyl acetate, successive and crude methanolic extracts was 1.36, 1.32, 3.69 and 5.97 %, respectively. This revealed that, polar solvents are more effective than less polar solvents to extract different secondary metabolites.
3. Contents of phenolics and flavonoids:
The highest content of phenolics was found in successive followed by crude methanolic, ethyl acetate and petroleum ether extracts, respectively. While the highest content of flavonoids was was found in crude methanolic followed by successive methanolic, ethyl acetate and petroleum ether extracts, respectively.