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العنوان
Routine Hysteroscopy before
First Intra Cytoplasmic Sperm Injection Cycle:
A Randomized Controlled Trial
/
المؤلف
Marey,Mohamed Hassan Ibrahim
هيئة الاعداد
باحث / محمد حســــــــــــــــــــن ابراهيم مرعي
مشرف / عمرو حســــــــــــــــــــــــن الشلقــــــــــانى
مشرف / أحــــمدالسيــــــــــــد حســــــــــن البهوتـــــى
مشرف / عمــــــرو حلمـــــــــــــــــــــــــى يحـــــــيي
الموضوع
Routine Hysteroscopy before<br>First Intra Cytoplasmic Sperm Injection Cycle<br>-
تاريخ النشر
2015
عدد الصفحات
129.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة عين شمس - كلية الطب - Obstetrics & Gynecology
الفهرس
Only 14 pages are availabe for public view

from 32

from 32

Abstract

Intra cytoplasmic sperm injection an expensive treatment but results in a successful outcome in only a third of treatment cycles. Assisted Reproductive Technology procedures for culturing and transferring embryos have been continually improved over the last two decades and the clinical pregnancy rate has not substantially improved over the last ten years. Implantation failure could be due to a variety of reasons including embryo quality and uterine receptivity but remains unexplained in many cases.
The presence of uterine pathology may negatively affect the chance of implantation. The prevalence of unsuspected uterine pathology in asymptomatic women with implantation failure has been reported to be as high as 50%. Hysteroscopy doesn’t only provide accurate visual assessment of the uterine cavity, but also gives a chance to treat any pathology detected during the examination and availability of hysteroscopy with smaller diameter has made the use of office hysteroscopy feasible as a routine examination.
There is evidence that performing hysteroscopy before starting ICSI treatment could increase the chance of pregnancy in the subsequent ICSI cycle in women who had one or more failed ICSI cycles. Infertility related to uterine cavity abnormalities has been estimated to be the causal factor in as many as 10% to 15% of couples seeking treatment. Moreover, abnormal uterine findings have been found in 34% to 62% of infertile women. Hysteroscopy is considered the gold standard for evaluating the uterine cavity, and due to improved endoscopic developments, can be performed reliably and safely as an office procedure.
Direct view of the uterine cavity offers a significant advantage over other blind or indirect diagnostic methods, although hysterosalpingography (HSG) is to be as accurate as hysteroscopy in the diagnosis of normal and abnormal cavities, the nature of the intrauterine filling defects is more accurately revealed by hysteroscopy. The correlation is only 65% between findings diagnosed with HSG compared with those diagnosed with hysteroscopy. Role of hysteroscopy in infertility investigation is to detect possible intrauterine changes that could interfere with implantation or growth, or both, of the conceptus, and to evaluate the benefit of different treatment modalities in restoring a normal endometrial environment.
Our study shows examination of about 170 patients of primary and secondary infertility of at least 1 year duration, Age: 19-35Years. We divided them into 2 groups, 85 patients underwent hysteroscopy before hyper stimulation of ovulation preceding ICSI cycle and 85 patients started their first ICSI cycle without a prior hysteroscopy.