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العنوان
Effect of Curcumin and Garlic on Adverse Effects of Gentamicin, Cefotaxime and Metronidazole in Male Rats /
المؤلف
El-Sayed, Ahmady Yousef Ahmed.
هيئة الاعداد
باحث / أحمدى يوسف أحمد السيد
مشرف / حسنى عبدالفضيل إبراهيم
مشرف / عبدالعليم فؤاد عبدالعليم
مشرف / يحيى أحمد اسماعيل رسلان
الموضوع
Gentamicin. Cefotaxime- Testing.
تاريخ النشر
2015.
عدد الصفحات
347 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
البيطري
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة الزقازيق - كلية الطب البيطرى - Pharmacology
الفهرس
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Abstract

This study was carried out to study the protective effect of curcumin (200mg/kg B.wt) and garlic (500 mg / kg B.wt) given orally on hepato-renal toxicity resulted from gentamicin (80 mg / kg.B.wt), Cefotaxime(540 mg/kg.B.wt) intramuscular with metronidazole (135mg/kg.B.wt)orally in male albino rats. Results indicated significant decrease in ( urea, creatinine, ALP, ALT, MDA and TNF-α) and significant increase in (albumin, total protein, GSH, Cat., SOD and GPx) that confirmed by histopathological and immunohistochemical reaction. we conclude that curcumin or garlic has protective effect against gentamicin , cefotaxime and metronidazole toxicity.