الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Skeletal muscle contractions power human body movements and are essential for maintaining stability. Skeletal muscle tissue accounts for almost half of the human body mass and, in addition to its power-generating role, is a crucial factor in maintaining homeostasis.
The term sarcopenia, coined by I. H. Rosenberg, originates from the Greek words sarx (flesh) and penia (loss). Although this term is applied clinically to denote loss of muscle mass, it is often used to describe both a set of cellular processes (denervation, mitochondrial dysfunction, inflammatory, and hormonal changes) and a set of outcomes such as decreased muscle strength, decreased mobility and function itamin D is a group of fat-soluble secosteroids responsible for enhancing intestinal absorption of calcium and phosphate. Although vitamin D is commonly called a vitamin, it is not actually an essential dietary vitamin in the strict sense, as it can be synthesized in adequate amounts by most mammals exposed to sunlight.
Vitamin D is well known for its important role in bone and mineral metabolism. It promotes calcium and phosphate absorption in the intestine and maintains an adequate concentration of these minerals in circulation to allow for normal bone mineralization. Accordingly, low vitamin D status is clinically associated with osteoporosis and fractures. Recently, many nonskeletal actions of vitamin D on cellular proliferation and differentiation, muscle function, and immunity have also been suggested
The study was carried out to identify the prevalence of sarcopenia and its relation to vitamin D.
First step was a cross sectional study to identify the prevalence of sarcopenia among male. And the second step is identify the relation between sarcopenia and vitamin D .The study enrolled 350 elderly males’ patients (60 years old and above) were recruited from outpatient clinic and inpatient wards of Ain Shams University Hospital age of the patients ranges from 60 to 85 years old mean age and the mean age of the studied population is 64.949 ±5.22.
The study was performed by assessing muscle mass and body composition using Bio Electrical Impedance Analysis (BIA) and assessing muscle performance by using hand grip strength by a Jammar handheld dynamometer where three trials done by both hands separated by 1 min between each trial and average of the dominant hand was taken. And muscle performance assessment was by the timed get-up-and-go (TGUG). Laboratorial Measurement of serum 25- Hydroxy Vitamin D by enzyme-linked immunosorbent assay (ELISA) technique and expressed as ng/mL.
Sarcopenic patients (24 patients from 350) represented 6.9% of the studied population while presarcopenia is 2.3%, while prevalence of sever sarcopenia is 5.9%.and sarcopenia was significantly correlated with vitamin D.
So it is recommended to consider Screening for sarcopenia for the early discovery of the disease to give time for early intervention and prevention,to do further further studies to understand the risk factors of sarcopenia that is related to our country, After identification of the risk factors of sarcopenia this might help in planning of prevention program for this prevalent disease, Screening for vitamin D deficiency among sarcopeinc patients and that Vitamin D supplementation for sarcopenic patients might be of great value either for reversibility or preventing further progression.