الفهرس 
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Abstract
ENGLISH SUMMARY
Fibro-osseous lesions of maxillofacial bones comprise a diverse group of
pathologic conditions whose subclassification is problematic. Among
these lesions, ossifying fibroma (OF), the commonest in fibro-osseous
lesions, promotes a substantial debate owing to the inexplicable range of
its variants. Given that OF embraces lesions of fibrocellular tissue and
mineralized material of varying appearances, this definition categorically
include ossifying fibromyxoid tumor, osseous choristoma of the
periodontium, ossifying variants of odontogenic fibroma and Nora’s
lesion.
This study enrolls ossifying fibromyxoid tumor as a variant of ossifying
fibromas toward contrast the similarities and differences in terms of
aggression, malignant potential, metastatic propensity, recurrence and
histological similitude. It evaluates, clinically and histochemically
(AgNOR stain), the aggression of different variants of ossifying fibroma;
elucidates the nature of ossifying fibromyxoid tumor and correlate the
findings with the contemporary surgical modalities of treatment.
The study used AgNOR as a histochemical stain to measure the
proliferation activity in contrast to clinicopathologic findings of 100
archival cases. Results provided measures for the MPC and MAF in the
different variants. The AgNOR expression was the lowest in the normal
mucosa. POF showed a very comparable picture of the normal mucosa.
The cases of COF showed much higher measures while the highest score
was obviously of OFMT. AgNOR stain was recommended to be routinely
recruited as an adjunct diagnostic tool. OFs encompass variants of
substantially diverse potential: reactive, benign and borderline malignant.
Therefore, a new taxonomy should be considered in order to cope with
such diversity.
Lesions of noticeable myxoid-rich hisological element, either central or
peripheral, should be assessed carefully with meticulous attention to
lymph nodes.
Psammomatoid ossifying fibroma was proved to be histochemically
similar to its related variant: TrOF.
With regard to recommended treatment options, simple excision is
indicated if the AgNOR score ranged from (50-100); the other treatment
modalities are indicated as follows: wide local deep excision (150-200),
marginal resection (200-1000), marginal resection, hemimaxillectomy or
hemimandiblectomy (1000-1500), total resection with reconstruction
(1500-2000) and neck dissection and lymph nodes should be considered
(if >2000).