الفهرس 
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Abstract
Campylobacter is the most commonbacterial cause of human gastroenteritis in many countries. In this study bacteriological examination of a total of one hundred and fifty samples (102 feces, 36 water and 12 food samples) werecollected from apparently healthy ostriches from different farms and zoo to identify Campylobacter species. The resultsrevealed thatCampylobacterspecies could be detected with an incidence of24.67%. It was clear that the highest isolation of Campylobacter species was 36.11% in water samples followed by food samples (25%) then fecal samples (20.59%). Zoo water samples had the highest isolation ratio (57.14%), followed by private farms (31.25%) and it couldn’t be detected in the governmental farms. The presented study elucidated that the Campylobacterjejuni(18%) and Campylobacter coli (6.67%) were identified. from the results it is cleared that a higher incidence rate of Campylobacterspecies was obtained during the warmer seasons than the cold one. The rat liver and intestine after infection with Campylobacterspecies revealed necrotic foci, edema and paleness of the rat intestine. Histopathological findings of the experimentally infected rats with Campylobacter species revealed destruction and necrosis of some intestinal glands with desquamation of epithelial cells covering superficial surfaces of the villi of the intestine, while in the rat liver showed foci of lymphocytic infiltrations and necrosis of hepatocytes with inflammatory cell aggregations at the portal area. In the present study, HSP70 was estimated among the collected rat sera infected with Campylobacter species using ELISA.It was clear that a significant difference in HSP70 readings between Campylobacter jejuniand coli infected groups and the negative control group in the first and second week of infection.