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العنوان
Intratympaic Injection of Steroids for Tinnitus Control /
المؤلف
Hussein, Marwa Mohamed Mahmoud.
هيئة الاعداد
باحث / مروه محمد محمود
مشرف / محمد أحمد محمود
مناقش / بدوي شحات بدوي
مناقش / أحمد عبد العليم عبد الوهاب
الموضوع
Otorhinolaryngology.
تاريخ النشر
2016.
عدد الصفحات
127 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الحنجرة
الناشر
تاريخ الإجازة
27/12/2016
مكان الإجازة
جامعة أسيوط - كلية الطب - Department of Otorhinolaryngology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Tinnitus is a common and distressing symptom that is characterized by the perceived sensation of sound without a corresponding external stimulus. Tinnitus can take the form of buzzing, hissing or ringing, or a combination of these or other characteristics. It can be heard in one or both ears, but it can also be referred to the head. Tinnitus can occur continuously, intermittently, or have a pulsatile character.
Tinnitus represents a highly prevalent and potentially distressing condition that transcends the classical definition of an otological illness to encompass a range of symptoms that are likely to place a huge burden on patients and significantly impair quality of life.
Tinnitus is marked by its individuality and heterogeneity for each patient.
Different hypothetical mechanisms were postulated for generation of tinnitus. As the mechanisms of tinnitus are not well understood, no effective treatment has been established yet. Many trials were done to solve this problem.
A focus on risk factors for each tinnitus patient provides an increased level of flexibility for interpretation of the clinical significance of the results of a treatment method and its future application for tinnitus relief.
This study was designed to evaluate efficacy of intratympanic corticosteroids injection in management of tinnitus patients with SNHL.
Thirty patients complaining of tinnitus with SNHL were evaluated (22 bilateral and 8 unilateral).
The equipment used were: audiometer Orbiter 922, audiometer Madson OB 822, tympanometer probe using Impedance audiometer AZ 26, evoked potential audiometry (Nicolet Spirit) version 2, Micromedical tech. version 8, spinal needle No. 22 and operating microscope.
All subjects in the study were submitted to:
- Full history taking
- Tinnitus questionnaire
- Otological examination
- Pure tone audiometry
- Speech audiometry
- Acoustic impedance measurements
- Tinnitus matching tests
- ABR to exclude retrocochlear affection
- Intratympanic injection of dexamethasone under operating microscope using spinal neddle NO. 22.
The evaluations were done in three sessions after intratympanic injection of steroids.
The results of pure tone thresholds showed that there was no statistically significant difference before and after the injection.
The result of speech discrimination showed that there was statistically significant difference before and after the injection in the form of increased discrimination.
Tinnitus measurements showed that there was statistically significant difference before and after the injection for two parameters, MML and loudness of tinnitus in the form of decreased MML and loudness.
Tinnitus questionnaire (THI) showed that there was statistically significant difference before and after the injection in the form of decreased the score of the questionnaire.
Accordingly it is recommended to use intratympanic injection of dexamethasone as a trial in management of tinnitus patients, and to apply tinnitus matching tests and tinnitus questionnaire (THI) as an outcomes measures to assess the efficacy of the injection.