![]() | Only 14 pages are availabe for public view |
Abstract Hepatic focal lesions may be benign or malignant. Therapy requires an accurate diagnosis regarding the nature and number of focal lesions, which in turn relies primarily on appropriate imaging techniques. MRI, having many sequences, markedly helps in the detection of small lesions and in reaching the diagnosis easily even without contrast injection or the need for biopsy as in cysts and hemangiomas. For hepatic focal lesions detection and characterization, conventional MRI relies on T1-weighted, T2-weighted, and dynamic gadolinium-enhanced T1-weighted imaging. Subtraction in the liver is an increasingly used additional software tool. It has the advantage of better assessment of contrast uptake which is an essential feature in characterization of hepatic focal lesions. In our study we concluded that using the subtraction with the standard MRI protocol is useful in better detection of malignant hepatic focal lesions with increased sensitivity, specificity and accuracy rates than standard MRI alone. Subtraction proved to be helpful in the detection and assessment of malignant focal lesions of the liver, but should always be used in conjunction with traditional MRI since there is risk of mis-registration errors being interpreted as enhancing tumour. |