الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Most antioxidants isolated from higher plants are polyphenols,
Phenolic compounds possess an effective inhibitory effect on cancer invasion and metastasis is also increasingly being reported in the scientific literature.
Several polyphenols were tested on MCF7 cells,Only gallic acidand quercetin showed prominent inhibitory effects on MCF7.
The cytotoxic properties of methoxy phenolic acid and it is derivatives, structurally related tothe natural models (gallic acid, Combretastatin A4) have been tested on MCF-7cells.
The net results show thatinhibitions of growth of MCF7 at 20µM are as following:
1- Compounds less than 80% inhibition of growth: (21, 29, 33, 34).
2- Compounds less than 90% inhibition of growth: (30).
The structure activity relationship of benzoic acid and it is methoxyderivatives on MCF7 cells at 20 µMwere illustrated in this thesis.