![]() | Only 14 pages are availabe for public view |
Abstract Squamous cell carcinoma accounts for the vast majority of malignancies of the oral cavity and oropharynx. It represents almost 95% of the head and neck cancers. Oral and oropharyngeal SCC imply quite significant mortality and morbidity rates. Adequate assessment of oral cavity and oropharynx malignancies is critical for appropriate planning of surgical, radiation, and chemotherapy treatment. This motivates the search of factors with prognostic relevance for better management of cancer patients. Staging provides information about the primary tumour as well as cervical lymph node metastasis which helps in making therapeutic decisions and has a prognostic values for the patient. One of the sources of information for pretreatment staging is imaging which is more accurate than physical examination. In addition few studies suggested that cross-sectional imaging can be useful in the assessment of other prognostic criteria such as the thickness (depth of invasion) of the primary tumour, the status of the regional lymph nodes including extracapsular (ECS) spread as well perineural spread and bone invasion. Of the imaging modalities, cross sectional images namely; CT and MRI are the most appropriate for the pretreatment staging of head and neck tumours. The aim of the present study was to correlate the accuracy of radiologic tumour thickness (RTT) using cross sectional imaging with the histological tumour thickness (HTT) in oral and oropharyngeal SCC and to determine the accuracy of cross sectional imaging in nodal staging and detection of ECS and finally to correlate the overall imaging-based staging with the final histologic diagnosis. Fifteen patients were included in this study. Clinical data of these cases were collected. Ten patients underwent contrast enhanced CT and five patients underwent MRI with contrast and complementary non contrast bone algorithm CT. The biopsies were histologically examined after hematoxylin and eosin staining. |