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Abstract -1- OVERVIEW: A renal stone are a kidney disease with varying worldwide prevalence. Stone formation and increasing in it is size is due to increasing in some substances concentrationshh89 in urine lead to decreasing it is dissolving and excretion inn urine and these are the main factors that contribute to cause renal stone are Genetic, Environmental, Personal habits and more importantly nutritional which responsibility the use of complementary and alternative medicines which in fact has increased in the past decade. Although there is a potential therapeutic benefits of complementary and alternative medicines on the other hand several studies show possible adverse outcome from use of some complementary and alternative medicines. There for it is essential to do enough studies in this medical field. 7-2- Aim of study: The main objective of present investigation was studying the effect of some foods on the health status of kidneys in rats inflicted with high phosphoric, uric and oxalic salts by using mustard seeds and watermelon. 7-3- MATERIALS AND METHODS 1. Investigated samples: Investigated samples of some tests plants such as mustard seeds powder and watermelon plup powder for protein, fat, moisture, ash and fiber. Carbohydrate was calculated by difference and determined of minerals contents. 2. Experimental animals (rats) Adult male albino rates (Sprague-Dawley Strain) n=64 weighting 130-170 g. 3. Induction of different high salts in experimental animals: 3-1: Induction of hyperuricemic rats by feeding rates on basal diet contained 30% Fructose for 10 Consecutive days. 3-2: Induction of hyperphosphatemic rats by feeding rats on basal diet contained glucose and fructose (15%) and caffeine (15%) replacement by starch for 10 consecutive days. 3-3: Induction of hyperoxaluric rats by feeding rats on basal diet contained mixture of cabbage broccoli (5%) sucrose (5%) and potassium permanganate (0.03%) for 10 consecutive days. 4. The diet and grouping of experimental animals (rats): The used of mustard seed and watermelon which added to Basel diet at 5%, 10%. All rats were fed on control diet for 6 consecutive days before the beginning of the experiment for adaptation. The rates were divided into four main groups as following: 4-1: Group 1 (-ve): negative control (normal rats): Fed on basal diet only as negative control for 28 days (n=4 healthy adult rats). 4-2 Group 2: Hyperuricemia Rats were pretreated with high of uric salts. This group consists of 4 rates as following: Group 1 (+ve): Fed on basal diet only as positive control for 28 days. Group 2: Fed on experimental diet which was containing 5% mustard seeds powder. Group 3: Fed on experimental diet which was containing 10% mustard seeds powder. Group 4: Fed on experimental diet which was containing 5% watermelon pulp powder. Group 5: Fed on experimental diet which was containing 10% watermelon pulp powder. 4-3 Group 3 : Hyperphosohatemia Rats were pretreated with high phosphoric salts. This group was subdivided into 5 subgroups each group consists of 4 rates as follows. Group 1 (+Ve) : Fed on basal diet only as positive control for 28 days. Group 2: Fed on experimental diet which was containing 5% mustard seeds powder. Group 3: Fed on experimental diet which was containing 10% mustard seeds powder. Group 4: Fed on experimental diet which was containing 5% watermelon pulp powder. |