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Abstract Deep vein thrombosis (DVT) is a popular and serious disease.It can lead to serious complication; the most fatal of them is pulmonary embolism (PE). Virchow’s triad is a group of 3 factors known to affect clot formation: rate of flow, the consistency (thickness) of the blood, and qualities of the vessel wall. Virchow noted that more deep venous thrombosis occurred in the left leg than in the right and proposed compression of the left common iliac vein by the overlying right common iliac artery as the underlying cause. The cornerstone of proper management of DVT is early diagnosis & prompts treatment. The diagnosis of DVT is not an easy process because most of clinical manifestations are not conclusive and shared with other diagnoses. The development of Wells scoring system improved a lot the ability of specialists in diagnosis of DVT. The diagnosis of DVT depends a lot on objective tests; the standard of them is duplex study of deep venous system. Duplex study equals the accuracy of venography but less invasive. Laboratory improvement in the study of coagulation system has been discovered unique product resulting from action of plasmin on cross-linked fibrin contained in the thrombus. Its detection depends upon monoclonal antibodies to epitopes on surface of D- dimer. Management of isolated calf vein thrombosis had a lot of controversy. In our study 40 patients had 10 days of therapy for isolated calf vein thrombosis and they were followed up by Duplex ultrasound and the and the results of 10 day regimen in both the provoked and unprovoked were satisfactory. |