الفهرس 
Ovarian Reserve and Prediction of Response to StimulationOnly 14 pages are availabe for public view
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Abstract
The aim of Superovulation for assisted conception treatment techniques is to induce women to produce a larger number of oocytes than the one or two that are required for normal ovulation induction programs . The use of gonadotropin-releasing hormone (GnRH) agonists with gonadotropins has resulted in greater ease of planning the Superovulation stimulation than was possible with the earlier use of clomiphene citrate (CC) with gonadotropins . That regimen had to be monitored carefully in order to predict and prevent the occurrence of an endogenous preovulatory LH surge. In the absence of GnRH analog controlled cycles there is a cancellation rate of 15-20% because oocyte retrieval has to be performed 26-28 hours after the detection of the endogenous LH surge this often meant that oocyte collections were performed at night and at weekends. The continuous administration of GnRH agonists (daily or depot application) initially causes LH and FSH hypersecretion (flare-up), which is followed after a period of about 10 days by desensitization of the pituitary and profound suppression of LH and FSH. This results in the inhibition of ovarian steroidogenesis and follicular growth. This ”medical hypophysectomy” has shown to be beneficial in reproductive steroid-dependent disorders and during IVF treatment to prevent a premature LH surge.