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العنوان
New Instrumental Methods For Determined OF Some Anti-Micorbial and Anti- Hypertensive Drugs /
المؤلف
Soliman,Basma El-Sayed Ghareeb.
هيئة الاعداد
باحث / بسمة السيد غريب سليمان
مشرف / عفاف أبوالخير
مشرف / هناء محمد صالح
مناقش / هشام شرف الدين
الموضوع
Antimicrobial drugs. Antihyperten sive drugs. Atenolol - Congresses.
تاريخ النشر
2015.
عدد الصفحات
262 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
الناشر
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة الزقازيق - كــليـــة الصيدلــــة - department of Analytical Chemistry.
الفهرس
Only 14 pages are availabe for public view

from 295

from 295

Abstract

Cerium (IV) ion was widely used for determination of many pharmaceutical compounds due to its oxidizing properties. Many reactions involved the use of cerium (IV) ion for the quantitative determination of different pharmaceuticals using different analytical techniques.
Diclofenac sodium [346], ritodrine hydrochloride and amoxicillin [347], phenolic -lactam antibiotics [348], risedronate sodium, alendronate sodium, etidronate disodium [349], nizatidine [350], ambroxol HCl and orciprenaline sulphate [351] were determined spectrophotometrically by measuring the decrease in cerium (IV) ion absorbance at 317 nm.
Isoxsuprine hydrochloride [352] and Indapamide [353], were also determined spectrofluorimetrically by measuring the fluorescence intensity of the resulting cerium (III) ion at 356-357 nm (excitation at 257 nm) was achieved.
Spectrofluorimetric and spectrophotometric methods for determination of ritodrine hydrochloride [354], penicillins, cephalosporins [355], aztreonam [356], acyclovir and acebutolol hydrochloride [357] were reported.
Spectrophotometric method was also applied where the residual cerium (IV) ions, were allowed to react with another reagent causing a decrease in reagent colour, this other reagent can be iron(II) thiocyanate for determination of propranolol [358] iron(II) with o-phenanthroline for determination of lansoprazole [359], methyl orange or indigo carmine for determination of ciprofloxacin [360], celestine blue for determination of olanzapine [361], and chromotrope 2R for determination of diltiazem HCl [362], ambroxol HCl, carbocisteine and orciprenaline sulphate [351].