الفهرس | Only 14 pages are availabe for public view |
Abstract Antioxidant drugs play a vital role in defense system in vivo against oxidative stress induced by free radicals and reactive oxidative species. Antioxidants are widely used in treatment or prophylaxis of many diseases such as, cardiovascular diseases, cancer, diabetes mellitus and ocular diseases. Strong antioxidants activities have been found in vitamin C, garlic and pomegranate. The present study was conducted to throw the light on the possible immune modulating effect of vitamin C, garlic and pomegranate beside their antioxidant effect. Twenty five adult male New Zealand rabbits of 2-3 months old and weighing 1.5kg each were classified into five equal groups, 5 rabbits each as follows: The first group: Rabbits received neither vaccine nor drugs and kept as control group. The second group: Rabbits were vaccinated on the 15th day from the beginning of the experiment (Formalinized killed P. multocida vaccine 1ml in the skin fold in the back of the New Zealand rabbit). The third group: Rabbits were given vitamin C at a dose of 6.3mg/1.5kg b.wt. I/P once daily for fourteen successive days and then vaccinated on the 15th day from the beginning of the experiment (Formalinized killed P. multocida vaccine 1 ml in the skin fold in the back of the New Zealand rabbit). |