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العنوان
Development Of Soft Gelatin Capsule Containing Poorly Soluble Drugs /
المؤلف
Komeil, Ibrahim Abdel Mohsen Abdel Kader.
هيئة الاعداد
باحث / ابراهيم عبد المحسن عبد القادر
مشرف / اسامة يوسف عبد الله
مشرف / احمد نبيل علام
مناقش / سناء الجيزاوى
الموضوع
Pharmaceutics.
تاريخ النشر
2014.
عدد الصفحات
144 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - Pharmaceutics.
الفهرس
Only 14 pages are availabe for public view

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from 183

Abstract

It is concluded the applicability of using a low cost a product containing 53% soybean phosphatidylcholine known as Phosal®53 MCT to optimize a nano delivery system to improve the systematic bioavailability for CUR. It was found that formulation of CUR to be solubilized in conduct the best way to deliver CUR as a parent compound into systematic circulation over other formulations which contain hydrophilic surfactants. Although good stability of such formulations upon storage in well closed containers, it shows a bad stability inside soft gelatin capsule due to possible interactions between shell contents and fill contents or due water migration phenomena. This issue may be improved in the future by further more studies to optimize the shell formulation to improve its ability to be filled with such viable formulations.