الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Acute kidney injury (AKI) is one of the most challenging and serious complications of pregnancy and postpartum period. Acute kidney injury in pregnancy continues to be common in developing countries. This work aimed to study positive cases of peripartum acute kidney injury, how to diagnose, manage each case and identify the factors related to the unfavorable evolution.
This study included 120 female patients during the peripartum period, divided into 2 groups; The acute kidney injury group of patients (AKI Group) included 49 patients (40.8%) and the non-acute kidney injury (Non AKI Group) group of patients included 71patients (59.2%).
All the studied groups were subjected to the following:
Complete history taking.
Thorough physical examination.
Laboratory Investigations that have included serum creatinine, blood urea nitrogen, arterial blood gases, serum albumin, prothrombin time, international normalize ratio(INR),Complete blood count, complete urine analysis and urine albumin to creatinine ratio.
The results of these study revealed the following:
There is no specific significant independent risk factor for AKI which means that the prediction of AKI is multi factorial such as hypertention, diabetes, preeclampsia, increased serum creatinine 48 hours postpartum and other factors. This means that the summation of more than one factor together increases the risk of AKI incidence in pregnant female.
The percentage of preeclampsia among AKI group is highly significant (83.7%) this means that the preeclampsia is one of the most common causes of peripartum AKI.
Delivery of the fetus is the recommended therapeutic option, with additional therapies indicated for each specific disease entity.
The outcome was favorable, with a complete renal function recovery for (71.4%) of patients.
Poor prognosis for mother and fetus and prediction of heamodialysis in AKI patients with DM, hypertension, increased serum creatinine 48 hrs post-partum and increased serum uric acid.
Fourteen patients (28.5% of AKI group of patients) who went heamodialysis were followed up after 6 weeks and up to 3 months of delivery which revealed that 6 (42.9%) patients recovered completely while 5 (35.7%) patients completely recovered, 2 (14.3%) patients became chronic kidney diseased patients’ and 1 (7.1%) patient became End Stage Renal Diseased patient after 3 months of follow up.