الفهرس 
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Abstract
The treatment of major burns has been the primary motivating
factor for the development of skin substitutes which have witnessed
several advancements so that have reflected on improvement of survival
rates and the resultant scars. In fact no ideal substitutes are available so
this demanded emergence of various ones.
Temporary skin substitutes are usually bilayer structures. There are
usually usedto close the wound, to protect it from environmental insults.
The current gold standard temporary skin substitute is split-thickness
allograft.
Permanent skin substitutes are used to replace full thickness skin
loss as well as to improve the quality of the skin.
Stem cells provide new hopes and expectations not only in healing
burn wounds but also in restore scarless regenerated skin so these cells
may in future obsolete all known methods of management today.
Early excision and closure of the wound reduces mortality and
morbidity in the severely burnt patient.
Selection which type of skin substitutes can be used must be
individualized to each patient according to several factors e.g. age,
general condition, previous or present medical diseases, associated
traumas, percentage of burn, depth of burn, availability of skin
substitutes, the cost and sometimes moral issues.