الفهرس 
Introduction
Epidemiology of Oral CancerOnly 14 pages are availabe for public view
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Abstract
The early diagnosis and management of carcinoma of the oral cavity is essential and it continues to present a great challenge. Carcinoma in an early stage of development is hard to detect clinically because the lesion may not be palpable and color of the lesional tissue is not necessarily different from the color of the surrounding mucosa.
The aim of the present study is finding out the most reliable and accurate method for early detection of precancerous oral lesions.
The present study compares between available techniques used for early detection of oral cancer and PML. Toulidine blue stain and brush exfoliative cytology results were compared with reference to incisional/excisional biopsy and histopathology.
TB test showed excellent sensitivity (100%) as it was positive in all cases that showed histopathology of oral cancer or PML, also showed high specificity (83.3%).
It was determined that if TB is used to screen high-risk populations, the likelihood of a false negative finding is extremely low, whereas false positive results will be relatively numerous.
Brush cytology showed low sensitivity (56.5%) with much false negative results and high specificity (100%).
Brush cytology results in the present study showed false negative results among patients with lesions diagnosed clinically as PML. However all cases showing clinical appearance of cancer give positive brush cytology results.
Oral cytologic test is highly sensitive and specific in detecting dysplastic changes in high-risk mucosal lesions (due to clinical findings suggestive of malignancy), but when used in a low risk population with benign-appearing oral epithelial lesions, the accuracy is reduced and the rate of false-negative findings increases.