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Abstract Endometriosis is a common benign gynecologic disorder defined as the presence of endometrial glands and stroma outside of the normal location. Endometriosis is a hormonally dependent disease and as a result is chiefly found in reproductive-aged women. Its symptoms are associated with work absenteeism, social isolation, and high costs of therapy. Most estimates of the prevalence of endometriosis have ranged between 5% and 20% among women with pelvic pain and between 20% and 40% among infertile women; a general prevalence ranging between 3% and 10% in reproductive-aged women is likely. Although the definitive cause of endometriosis remains unknown, several theories with supporting evidence have been described.It is currently recognized that genetic, anatomic, endocrine, immunologic, and possibly environmental factors influence the risk of developing endometriosis. A definitive diagnosis of endometriosis continues to be based on histologic examination.The histologic diagnosis of endometriosis is based on the typical presence of both endometriotic glands and stroma. Endometriosis may develop anywhere within the pelvis and on other extrapelvic peritoneal surfaces. Most commonly, endometriosis is found in the dependent areas of the pelvis; The ovary, pelvic peritoneum, anterior and posterior cul-de-sac, and uterosacral ligaments. |