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Abstract Asthma is a chronic inflammatory disorder of the airways characterized by an obstruction of airflow, which may be completely or partially reversed with or without specific therapy. Airway inflammation is the result of interaction between various cells, cellular elements and cytokines. In susceptible individuals, airway inflammation may cause recurrent or persistent bronchospasm, which causes symptoms including wheezing, breathlessness, chest tightness and cough, particular at night or after exercise. Asthma prevalence has increased very considerably in recent decades such that it is now one of the commonest chronic disorders in the world. Asthma is caused by environmental and genetic factors. These factors influence how severe asthma is and how will it responds to medication. |