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العنوان
Evaluation of Faecal Calprotectin as a Valuable Non invasive Marker in Distinguishing Gut Pathogens in Young Children with Acute Gastroenteritis /
المؤلف
Abd El Rahim, Ahmed Fawzy Negm.
هيئة الاعداد
باحث / أحمد فوزي نجم عبد الرحيم
مشرف / نبيل محمد جميل
مشرف / أسامة جلال
مشرف / محمود الريحانى
الموضوع
Pediatrics. Child. Infant.
تاريخ النشر
2013.
عدد الصفحات
59 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة المنيا - كلية الطب - الاطفال
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present study aimed to evaluate fecal calprotectin as a valuable non invasive marker in distinguishing gut pathogens in young children with acute gastroenteritis as early predictor of bacterial inflammation. The study was carried on 90 child (1-36 months ) selected from the Pediatric Department of Children’s University Hospital at Minia University during the time period from June 2012 to December 2012.
Studied infants and children were divided into ; Group A (acute gastroenteritis = AG ) ; A1- BAG (bacterial growth were found in 19 cases as follow ; 6 proteus spp ,6 salmonella spp , 4 E-Coli ,3 shigella spp). A2- NBAG (no bacterial growth were found in this group = 41 cases
Group B ( controls ) It consists of 30 child aged 1-36 months divided in two groups as Follows ; 1- infants (1-12 months ) . 2- young children (12-36 months ) . All children included in the study were subjected to Full history taking , thorough clinical examination, laboratory investigation as ESR, CRP and WBCs . stool culture was done to detect bacterial growth and f-cp was measured in stools by ELISA technique .
Results:
1- f-cp is higher in BAG than NBAG and controls;
• The median and IQR in BAG are 225.61(198.72-263.28) ,
• The median and IQR in NBAG are 59.76(51.95-69.76) ,
• The median and IQR in controls are 36.31(32.71-37.22) ,
2- CRP is higher in BAG than NBAG ;
The median and IQR in BAG are 48 (36-90)
The median and IQR in NBAG are 5 (3-7.5)
3- ESR is higher in BAG than NBAG ;
The median and IQR in BAG are 22(18-34)
The median and IQR in NBAG are 6(4-9)
4- WBCs are higher in BAG than NBAG
The median and IQR in BAG are 11.80(10.60-13.10)
The median and IQR in NBAG are 5.20±(4.80-7.85)