الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Conventional non-surgical periodontal therapy has been proven to be an effective treatment for patients with chronic periodontitis.Local administration of antimicrobials provides a high concentration of the drug in the pocket and enhances the clinical results without any systemic side effects and bacterial resistance. Azithromycin (AZM) is a semi-synthetic,acid-stable antibiotic, has unique characteristics that support its use as adjunct to conventional therapy in the treatment of chronic periodontitis. The aim of this study was to determine in-vivo the effect of 0.5% AZM gel clinically, microbiologically and immunologically in the treatment ofmoderate to severe chronic periodontitis. |