الفهرس | Only 14 pages are availabe for public view |
Abstract The reaction of 2-cyano-N’-(pyridin-4-ylmethylene) acetohydrazide (1) with phenyl isothiocyanate gave thiocarbamoyl derivative 3 which reacted with α‐halocarbonyl compounds in N,N‐dimethyl formamide in the presence of triethyl amine to afford thiazoles 6, 9, 11, 13, 15 and thiophene 8 derivatives, while when the same reaction was stirred in N,N‐dimethyl formamide, it only afforded the acyclic compounds 4, 7, 10, 12 and 14 which when refluxed in N,N‐dimethyl formamide in the presence of triethyl amine, they gave the corresponding above thiazole and thiophene derivatives. The newly synthesized compounds were characterized by analytical and spectral data. |