الفهرس 
Introduction and Aim of the Work
Anatomy of ColonOnly 14 pages are availabe for public view
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Abstract
The colon is a part of the digestive tract where food is processed to rid the body of waste. The first part of the large intestine, called the colon absorbs water and nutrients from food and stores waste matter. Colon cancer is one of the most common cancers worldwide and it is the fourth most diagnosed cancer in the world. 1,2-dimethylhydrazine is a known carcinogen which induce colon cancer in rats. DMH is derived from the natural toxin cycasin and extensively used to induce cancers in experiments with rodents.
Natural products play an important role nowadays in the prevention and treatment of number of cancers which spread over the entire world. Those natural products have many advantages more than chemotherapy; therefore our study focuses on natural products and its possible role as a preventive and therapeutic agent for cancers.
The present study was conducted in the Departments of Medical Biochemistry of both Faculty of Medicine, Assiut University and Faculty of Pharmacy, Al-Azhar University. The study included 60 male rats were divided into 6 groups (control, carcinogenic, prophylactic, treated with soybean, self limited and treated with 5-FU groups). Each group contained 10 rats which were euthanized by cervical dislocation. All rats were matched in age, weight and sex. Any rats suffering from general illness before injection, excess excitation after injection and recently injected with any other drug else, were excluded.
Galectins are growing family of evolutionarily conserved proteins widely distributed in nature from lower invertebrates to mammals. Gal-3 is a member of the galectin family, which consists of animal lectins that bind β-galactosides. Despite considerable researches, Gal-3 remains a new discovered glycoprotein which has several functions.