الفهرس 
NON MELANOMA SKIN CANCERS
Basal Cell CarcinomaOnly 14 pages are availabe for public view
 |  | from | 172 |  |  |
| | | from | 172 | | |
Abstract
The term NMSC can theoretically be applied to all cutaneous cancers excluding melanoma however; it is most commonly used to refer to the two major types of skin cancers; BCC and SCC. Other less common NMSC types include SK and KA.Aquaporins are a family of small, hydrophobic, integral membrane proteins that act primarily as waters elective pores, facilitating osmotically driven water transport across cell plasma membranes. There are at least 13 mammalian AQPs.Aquaporin-3, an aquaglyceroporinis found in the plasma membrane in the basal cell layer of the epidermis, as well as suprabasal layers, and is aefficient transporter of glycerol and water. It is a key player in epidermal biology. AQP3 null mice exhibit reduced epidermal glycerol content,impaired skin elasticity, delayed barrier recovery following SC removal and delayed wound healing. This suggests that AQP3 plays a role in differentiation and proliferation of keratinocytes.So, the aim of this work was to study the expression of AQP3 .