الفهرس 
Cover Page Title in EnglishOnly 14 pages are availabe for public view
 |  | from | 121 |  |  |
| | | from | 121 | | |
Abstract
Salmonella enteritidis is an important zoonotic disease. It plays a critical role in human health as major cause of food-borne diseases through contaminated eggs and chicken meat with parallel importance in poultry industry through verities of damage including high mortalities, , dramatic losses in egg production together with reduced fertility and hatchability besides bad body gain and high rate of condemnation. Control methods to such disease in chicken are a big deal either in human health or for poultry industry which include the use of intestinal flora preparations, acidifiers, antibiotics and vaccination. This work was studying the protective effect of the commercially available SE bacterin in protecting broiler breeders against the experimental infection, regarding effect on the productive performance, shedding of the challenged (SE) organism and reisolation from egg shell and yolk together with reisolation from non fertile and non hatched eggs accompanied by serological monitoring of the experimental hens before and after challenge. It was also studying the effect of the maternal immunity of the commercially available SE bacterin in protecting day old chicks against the experimental infection, regarding clinical signs ,mortalities, shedding of the challenged SE organism, reisolation from the internal organs of freshly dead and killed chicks from this study it could be concluded that1- The vaccination process had a negative effect on weekly egg production but it has a positive effect during the period of the challenge.- The administration of vaccine with either one or two doses had a significant role in decreasing the shedding of the challenged organism from the vaccinated challenged breeders. The vaccine had a role in decreasing the contamination of the egg shell and yolk with challenged SE organism with advantage to the double dose vaccinated than a single vaccinated vaccinated hens- One dose of the vaccine had a role in decreasing the reisolation from the non fertile and non hatched eggs, while the double dose of the vaccine had a role in preventing reisolation of the challenged SE from non fertile and non hatched eggs- Better MT and CV were obtained from double dose vaccination compared to single vaccination using specific ELISA kites against SE. Generally serological results using specific ELISA kites were correlated with protection parameters against experimental infection-The chick mortalities from a day-old to 14 day old were not affected by vaccination of hens but affected by the dose of challenge-Maternal immunity against SE had a positive effect on shedding of the challenged SE in chicks from vaccinated hens especially in low dose challenged group-Regarding the reisolation of the challenged SE organism from both freshly dead and killed chicks, were better in the chicks from vaccinated breeders in the group of high dose challenge-The vaccine showed a good role to protect the broiler breeders against the experimental infection regarding shedding , egg contamination and reisolation from non fertile and non hatched eggs with double dose but should be applied before start of laying to avoid the negative effect on performance. -The maternal immunity has a role in protecting their day old chicks against experimental infection regarding shedding and reisolation from internal organs with other protecting methods to control the disease-Serological monitoring may be considered as a screen test for vaccine or infection and may be considered as a screen test for protection in hens.