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Abstract SUMMARY AND CONCLUSION This experiment was designed to evaluate the use of egg yolk immunoglobulin as alternative to some vaccinations in broiler chicks. Fife hundred one day Hubbard and Cobb broiler chicks were divided in four experimental groups with: control group of Hubbared and treatment 1injected egg yolk containing immunoglobulin against IBDV + NDV, Cobb control and group 2 injected egg yolk containing immunoglobulin against IBDV + NDV. The main results could be summarized as follows: At marketing age there was no significant difference among treated groups for body weight at one-week old. It was concluded that the marketing weight (6wk) of Cobb broiler chicks was significantly heavier than that of Hubbard ones. The results in corresponding table were 1966.12 and 1910.66g for Cobb and Hubbard broiler chick, respectably. • During the period from the 3rd and 5th weeks of age the results showed that the treated groups injected with egg yolk immunoglobulin agents IBDV + NDV were significantly heaviest than that of control group. • It could be observed that the egg yolk containing immunoglobulin against NDV or IBDV + NDV significantly decreased the relative inedible meat parts compared to remaining groups. • from 28 to 42 days of age, it could be noticed that the Cobb broiler chicks were significantly consumed less feed compared to the remaining groups. The mean feed consumptions of Cobb control and IBDV+NDV group for mentioned experimental period (14-42 day) were only 3378.2, 3332.3 , 3255.4 and 3188.4 g of that consumed by Hubbard control and IBDV+NDV group broiler chicks respectively. • The IBDV + NDV group of Cobb strain was significantly higher relative body weight compared to other group (IBDV + NDV Hubbared). Concerning feather percentage, it could be noticed that the IBDV + NDV group recorded the lowest values 6.82 % compared to remaining control groups and another treatment. • Our results showed that the broiler chicks (Cobb and Hubbared) injected by egg yolk containing immunoglobulin against IBDV+NDV. Recorded higher dressing percentage values compared to other groups. • There was no significant difference among treated groups for relative gizzard weight. Conversely, the relative heart weight was significantly affected by treatment, where the broiler chicks injected by egg yolk containing immunoglobulin against NDV or IBDV + NDV were significantly higher relative heart weightcompared to other groups. • It could be noticed that the broiler chicks injected egg yolk containing immunoglobulin against IBDV+ NDV and combination recorded the highest hemoglobin and Hematocrit level compared to control group of hubbared .With respect to changes in lymphoid organs weight, the present results showed that the relative bursa weight was significantly decreased in groups injected with IgY against IBDV or IBDV + NDV compared to controlgroup. • The absolute and relative spleen weight didn’t significantly affected by treatment. Opposite trend was noticed for thymus weight, whereas the birds injected with IgY against IBDV or NDV had significantly higher relative thymus weight compared to other groups. • The present result in fig. 21 indicated that the Hubbard broiler chicks control had significantly lowest mortality number compared to all groups broiler chicks. However, the Cobb broiler control and treatment (IBD+NDB) Hubbared chicks were intermediate. • The present results indicated thahe antibody titer measured at 21 and 35 days of age against IBD+ NDV for cobb control was significantly highest than those of other groups. However, at 35 days of age, the hubbared control was significantly lowest antibody titer against IBD+NDV compared to control and tread. • At 35 days of age, our result showed that the control group recorded the highest antibody titer against IBD+NDV compared to remaining groups. The same trend was not observed at 35 days of age |