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العنوان
Potential therapeutic effect of cluster of
differentiation (CD34+ versus CD34-)
stem cell on the adult female rats
subjected to cerebellar damage induced
by monosodium glutamate /
المؤلف
Arafat, Horeya Erfan Korayem.
هيئة الاعداد
باحث / حورية عرفان كريم عرفات
مشرف / سمية محمد
مشرف / ماجدة نعيم
مشرف / سها يونس
مشرف / محمد عبده
الموضوع
monosodium glutamate.
تاريخ النشر
2013.
عدد الصفحات
171 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأنسجة
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة قناة السويس - كلية الطب - هيستولوجى
الفهرس
Only 14 pages are availabe for public view

from 171

from 171

Abstract

MSG consumption has some deleterious effects on the
cerebellum of adult rats at higher doses and by extension can
affect the functions of the cerebellum. The pathogenesis of
cerebellar ataxia is continuously expanding. Identification of
mechanisms underlying cerebellar disorders represents a
combination of key factors for the development of anti-ataxic
innovative therapies.
Traditional treatment of neurological lesions represents a
medical challenge but in recent years, new cell replacement
therapy has received considerable attention, intensified by
increasing number of potential cell sources for transplantation.
The stem cells used in most of the previous studies were injected
locally into cerebellar hemispheres but, little information is
available regarding the therapeutic potential of systemically
delivered cells on cerebellar ataxia.
Aim of the work:
This study was designed to improve the cerebellar
damage induced by monosodium glutamate by using
human umbilical cord blood stem cells; CD34+ versus
CD34- in adult female rats.