الفهرس 
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Abstract
Colorectal Cancer Is The Most Common Gastrointestinal Malignancy All Over The World. According To Cancer Statistics In National Cancer Institute (NCI) In Egypt, Colorectal Cancer Represents The 6th Most Common Cancer In Male And The 4th In Female from All Cancer Patients. With 3, 9% Mortality Rate from All Colorectal Cases .As With Many Types Of Cancer, Death from Colorectal Cancer Is Often A Result Of Metastatic Disease. Over One-Half Of Patients Who Die Of Colorectal Cancer Have Liver Metastases At Autopsy, And The Majority Of These Patients Die As A Result Of Their Metastatic Liver Disease. But Unlike Many Other Types Of Cancer, The Presence Of Distant Metastases from Colorectal Cancer Does Not Preclude Curative Treatment. Resection Of Hepatic Metastases from Colorectal Cancer Offers The Best Chance Of Long-Term Survival. Unfortunately The Majority Of Patients With Colorectal Hepatic Metastases Are Not Suitable For Resection And Therefore Specific Criteria Should Be Used To select Those Who May Benefit from Such Intervention. Many Different Non-Invasive Imaging Modalities Are Available For The Visualization Of Liver Metastasis. The Options Include Computed Tomography (CT), Magnetic Resonance (MR) Imaging, Ultrasound (US) And PET (Positron Emission Tomography Using Fluorine-18 Labelled Fluorodeoxy-Glucose). To Improve The Results Of Surgery, A Subgroup Of These Patients Either Receive Neoadjuvant Or Adjuvant Chemotherapy. Patients Not Suitable For Surgery, Due To Extensive Liver Metastases Or Extrahepatic Diseases, In General Undergo Systemic Chemotherapy. Several Newer Therapies Such As Cryosurgery, Radiofrequency Ablation (RFA), Portal Vein Embolisation And Two Staged Hepatectomy Are Being Evaluated In Patients Not Suitable For Surgery Due To The Number Or Distribution Of Liver Metastases. In Conclusion, Surgery Is The Most Effective Form Of Therapy For CRLM. Recent Advances In Imaging Modalities Have Helped In Better Patient selection For Surgery. Newer Chemotherapeutic Agents And Surgical And Radiological Interventions Have Meant That An Increasing Number Of Patients Can Now Be Considered Suitable For Surgical Resection.