الفهرس 
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Abstract
This study aimed to evaluate the relationship of plasma fetuin-A levels with markers of bone turnover (DEXA) scan in post-menopausal female type 2 diabetic subjects.
The study included 100 postmenopausal female divided in to 2 groups; the diabetic group included 70 patients and the non-diabetic group included 30 healthy controlled.
All patients underwent the following:-
Complete history taking.
Laboratory investigations that have included the measurement of serum level of fetuin-A, FBS, PP2H, HBA1c,CBC,ALP, ALT and AST, thyroid, parathyroid hormones,urea and creatinine.
Radiological assessment: DXA (the dual- energy x- ray absorptiometry) method for spine, hip, distal radius.
The results of this study revealed the following:-
Patient characteristics are presented in Table1 Demographical characteristics of the two groups were similar including age, disease duration and postmenopausal duration.
Serum fetuin-A levels were found to be significantly higher in the diabetic group (304.94 ± 21.85 ng) than in the control 1 group (109.21 ± 7.94 ng) (P < 0.001) .
Also we found that negative correlation between fetuin-A levels and lumbar spine (r = -0.314) (P = <0.05) BMD in the diabetic group. Additionally negatively correlated between FBS and BMD of hip area (<0.05)
Also 2hpp and HBA1c negatively correlated with BMD of spinal area (<0.05).
In our work osteoporosis represent 13.3% in wrist area and 8.9% in spin and hip areas in diabetic patients. While osteopeniawere found in 68.9%, 53.4%, and 35.6% in diabetic patients in spine, wrist, and hip respectively.
Osteopenia was found to be more prevalent than osteoporosis among elderly women with type II diabetes representing 68.9%, 53.4% and 35.6% in spine, wrist and hip respectively.