الفهرس | Only 14 pages are availabe for public view |
Abstract Cholinesterase inhibitors poisoning is still a global problem especially in the developing countries as Egypt. Cholinesterase inhibitors compounds are widely used as pesticides in agriculture and also as domestic insecticides. Patients may be exposed to cholinesterase inhibitors compounds through inhalation, ingestion or dermal exposure. The easy availability of these compounds and their wide spread usage makes self-poisoning by cholinesterase inhibitors compounds a common way for suicidal attacks especially in the young age group or by accidental ingestion especially in children. The present work aimed to evaluate the role of serum β-glucuronidase level as probable marker for the assessment of acute cholinesterase enzyme inhibitor insecticides poisoning. The present study was carried out on 60 patients of acute poisoning by cholinesterase enzyme inhibitors insecticides admitted to Alexandria Poison Treatment Unit and Critical Care Medicine Department in Alexandria Main University Hospital. Another 15 healthy volunteers were included as control group. All the cases were subjected to: thorough history taking, full clinical examination, grading of poisoning severity score (PSS), laboratory investigations (ABG, serum cholinesterase activity level (CHE) and serum β-glucuronidase level (βG). The present study showed that 53.3% of cases were females and 46.7% were males, with female |