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العنوان
CLOMIPHENE CITRATE AND HUMAN CHORIONIC GONADOTROPIN IN INDUCTION OF OVULATION/
المؤلف
Abd El Aziz, Shereen Mostafa.
هيئة الاعداد
مشرف / Mohamed Ahmed El Kadi
مشرف / Amr Mohamed El Helaly
مناقش / Mohamed Ahmed El Kadi
مناقش / Amr Mohamed El Helaly
تاريخ النشر
2013.
عدد الصفحات
136P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة عين شمس - كلية الطب - النسا والتوليد
الفهرس
Only 14 pages are availabe for public view

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Abstract

The study was conducted at the infertility clinic of Ain Shams Maternity Hospital during period from December 2011 to December 2012.
All patients in the study were complaining of inability to conceive and most of them (90%) have menstrual irregularities in form of oligomenorrhea (70.7%) or amenorrhea (19.3%) while a few have regular cycles (10%).
The patients were divided into two groups, each group includes 75 patients.
Group A: received CC only.
Group B: received CC plus HCG (pregnyl 10000 IU IM) to trigger ovulation when one or more follicles reached 18-22 mm in diameter,
Incidence of oligomenorrhea was 70% (106 out of 150 cases).
The incidence of amenorrhea in this study was much less 19% (29 cases out of 150 cases), The incidence of hirsuitism in this study was 19% (29 cases out of 150 cases), the mean values of FSH and LH in day 2 of the menstrual cycle were about 5.07 IU/mL and 8.89 IU/mL, respectively. There were no significant differences in the mean FSH or LH values of women in the two groups,
There were no significant differences between women of both groups regarding the duration and type of infertility as the
mean of the duration of infertility was 1.6 years in group A and 1.9 years in group B.
This study shows success of ovulation in patients after treatment with CC; 113 ovulated out of 150 women. In this study, there is no significant differences in ovulation rate between group A (70%) and B (80%).
There was no significant difference between women of both groups regarding the number of mature follicles, The proportion of women with evidence of ovulation (midluteal serum progesterone 3 ng/mL) was insignificantly higher in group B than in group A (84% in group B vs 73.3% in group A)
The mean midluteal serum progesterone was significantly higher in group B (14.04 ng/ml) compared to group A (9.44 ng/ml), the number of women who got pregnant in group A was 4 of 75 but in group B was 7 of 75.
The proportion of women with successful pregnancy was insignificantly higher in group B compared to group A (9.33vs 5.33%, respectively).