الفهرس 
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Abstract
Polycystic ovary syndrome (PCOS) is one of the most common female endocrine disorders, produces symptoms in approximately 5% to 10% of women of reproductive age (12–45 years old). It is thought to be one of the leading causes of female subfertility.(4,6)
PCOS is a complex, heterogeneous disorder of uncertain etiology, but there is strong evidence that it can to a large degree be classified as a genetic disease.(1-3) It was also found that the syndrome is familial and various aspects of it may be differentially inherited.
Considerable knowledge of the prevalence, pathophysiology and management of the syndrome has been gained.
The definition of PCOS has been much debated. In 2003 a consensus workshop sponsored by ESHRE/ASRM in Rotterdam indicated PCOS to be present if any 2 out of 3 criteria are met.
1. Oligoovulation and/or anovulation: (oligo menorrhea: 40 days or longer between the menstrual periods and/or Amenorrhea: absence of menstruation for > 3 cycles without being pregnant).(7-9)
2. Excess androgen activity: (clinically in the form of hirsutism, acne, clitromegally, masculinization, deepening of voice, increased libido or biochemically in the form of increased total and free testosterone level).
3. Polycystic ovaries (by gynecologic ultrasound): These have been defined and include either 12 or more follicles measuring 2-9 mm in diameter or increased ovarian volume more than 10 cm3.(5,7)
A diagnosis of PCOS carries lifelong implications for a women’s health and well-being. The diagnosis implies an increased risk of metabolic syndrome, cardiovascular disease, cancer, infertility and pregnancy complications for the women and her offspring.
The medical management of PCOS can be broken down into four components, three of which are ״acute ״ issues (control of irregular menses, treatment of hirsutism and management of infertility) and one that is more ״chronic ״ this latter issue may be the most important but least remembered by patients and providers a like i:e management may change; however, a continuous life –long management approach is important for the insulin resistance of PCOS.
The presenting symptoms dictate the management strategy for women with PCOS. To a large extent, the type of treatment is dependent on whether infertility is the main complaint or not.