الفهرس 
Childhood obesityOnly 14 pages are availabe for public view
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Abstract
Summary and Conclusion
The purpose of this study was to asses different indices of obesity,
metabolic syndrome, as well as related dietary pattern and to study the
level of serum vaspin as an indicator of insulin resistance in obese non
diabetic children.
This case-control study included forty-five obese (>95th BMI
percentile) non-diabetic children. All cases underwent clinical,
anthropometric, laboratory and dietary intake evaluation. Their data were
compared to forty-five ages and sex matched healthy lean controls.
Metabolic syndrome was diagnosed using definition developed by United
State National Cholesterol Education program (NCEP) and its modified
cutoffs for children. Insulin resistance was evaluated using HOMA and
serum vaspin level was measured for all cases and control.
Most of the cases (93.3%) were exceeding the 90th percentile of
waist circumference. Twenty-one cases had high systolic and diastolic
blood pressure over 90th percentile. Metabolic syndrome was highly
prevalent among obese children (53.3%). Thirty-one cases were on prediabetic
level of HBA1c. Insulin resistance was detected in 47.7% of
cases and acanthosis nigrican was found in 68.9% of obese children.
High serum vaspin level was found in 24 cases, with no statistical
significant difference between cases and control or between males and
females group.
There was statistical significant difference as regard energy
consumption between female group of cases and control, also the
difference was significant between male group of cases and control in
fibers consumption. Carbohydrates consumption was over
recommendation in 72.7% of male cases and 73.9% of female cases.
There was significant difference between cases and control as regarding
fibers consumption in 4-8 years old age groups; around one third of cases
had over calories consumption in the same age group; while 83.3% of 9-
12 years old and 100% of 13-15 years old age had carbohydrate
consumption over recommendations.
In conclusion, prevalence of the metabolic syndrome is high
among obese children, and it increases with worsening obesity.
Biomarkers of increased risk of cardiovascular and diabetic outcomes are
already present in these children. Body fat in obese children does not
influence serum vaspin levels. Serum vaspin level is not correlated
neither to metabolic syndrome markers nor insulin resistance. The
majority of Egyptian children-especially obese-eating patterns, as
measured by this study, need improvement