الفهرس 
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Abstract
INTRODUCTION
Caffeine and nicotine are worldwide known socially accepted drugs in most
countries. Due to their being addictive when they are ingested or inhaled, societies
from developed countries found it necessary to control their use and availability to a
certain extent. This was generally attained through advertisement for example or
through production of products with attenuated nicotine or caffeine content.
Nevertheless, their being used on a daily basis without prescription to increase the
sense of well-being and mood-altering contributes to their hazardous effects.
Caffeine is a CNS stimulant that is used in an abused manner. It acts through
the inhibition of the enzyme phosphodiesterase resutling in higher levels of cAMP.
Nicotine is a cholinomimetic drug that activates parasympathetic nervous system
through release of acetylcholine that can interact with receptors on sympathetic
nerves inhibiting the release of norepinephrine.
Nicotine is present in cigarretes and as a constituent of insecticides where acute
nicotine poisoning may occur during spraying. Cigarette smokers are usually coffee
drinkers. Through the great zest initiated in man to both drugs, acquired tolerance
might develop leading to drug dependence. Eventually habituation and psychological
dependence i.e. psychic craving, are indorsed. This is usually the case widely spread
among young adult individuals to overcome emotional distress .
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