الفهرس 
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Abstract
In this investigation, when 10H-phenothiazine (1) was treated with 2-
chloroacetonitrile, the corresponding 2-( 1 OH-phenothiazin- 10-y1)acetonitrile (69)
was obtained in 82 % yield (Scheme I).
a ;+ s 1”Ac”eto ne- a’n H N\\ I
N\ 4
69
Scheme 1
Refluxing of 69 with sodium azide in DMF and in the presence of
ammonium chloride afforded the corresponding tetrazole derivative 70 in 62 %
yield (Scheme 2).
70
Scheme 2
A mixture of 69 and hydrazine hydrate in dry ethanol was refluxed to give
the acetimidohydrazide derivative 71 in 76 % yield (Scheme 3).
Carbon disulfide was added to a solution of 71 in MeOH and the mixture
was refluxed for 12 h to afford the thione derivative 72 in 82 % yield (Scheme 4).
Scheme 4
A mixture of 71 and triethylorthoformate in ethanol was refluxed for 24 h to
give the corresponding 1,2,4-triazole derivative 73 in 76 % yield (Scheme 5).
Triethylorthof ormate
Scheme 5
Carbon disulfide was added to a solution of 71 in MeOH and the mixture
was refluxed for 12 h to afford the thione derivative 72 in 82 % yield (Scheme 4).
Scheme 4
A mixture of 71 and triethylorthoformate in ethanol was refluxed for 24 h to
give the corresponding 1,2,4-triazole derivative 73 in 76 % yield (Scheme 5).
Triethylorthof ormate
Scheme 5