الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
1 NTRODUC1’! ON
.Amines are organic compounds derived frorr. orrtmonia
with one or more of the hydrogen atoms replacef by an
alkyl or Aryl <JrOU!’
odors and difticu1tie5
1,2
identification •
They are known for obiectionable
associated with their isolation and
.One class of amines 1s becorr.1no
especially known because a numoer oi its members are
carcinogenic, these are the nitrosamines. Nonvolatile
amines also are receiving considerable research attention
because of important physiological effects they rr.ay induce
3
in humans and aminals. . Such amines are called biogenic
amines, and we will consider two in particular-histamine
and tyramine,
4
foods.
because they occur in cheese and other
The toxic dose is variable with individ~als
dependinq on efficie~cy of detoxifica~ion by conversic~ to
an aldehyde throuoh action of monoamine oxidase. In fact,
the use of certain druos called monoamine oxidase
inhibitors in psyctdatric ~ractice has been restricted
because of the occurrence of these a~ines food.
particularly cneese; the ’’cheese effect’’ therefore, is
known well wherein ingestion of certain drugs and chesse
may provoke hypertensive crisis and even death from
5,6
cerebral hemorrhage.
7