الفهرس 
Virus hepatitisOnly 14 pages are availabe for public view
 |  | from | 229 |  |  |
| | | from | 229 | | |
Abstract
Introduction and Aim of the Work
There arc rich interactions between the thyroid gland and
the liver. TI1e liver contributes significantly to the thyroid
economy through its control of hormone metabolism. The liver
is intimately involved in thyroid physiology via conversion of
tetra-iodothyronine (T4) to tri-iodothyronine (T3), conjugation
and biliary excretion of thyroid hormones and as the major
production site of the thyroid binding globulin affecting the
concentration of these hormones in blood. On the other hand ,
hyperthyroidism and hypothyroidism can present with hepatic
manifestations. Hyperthyroidism may be associated with
elevation of alanine aminotransferase and alkaline phosphatase.
which is mainly of bone origin. Hypothyroidism may be
a’sociated with elevation of aspartate aminotransferase (Fong et
a] . 1992). Jaundice may occur in hyperthyroidism (Thompson
et a! . 1994 ). Finally . in a number of viral and autoimmune
disorders both the liver and thyroid are affected
simultaneously (Salata et a] . 1985) . and thyroid dysfunction is
among the most commonly encountered immunological
disorders in patients 11 ith autoimmune hepatitis (Krawitt et al.
jl)l)(l J.
The aim of the present study was to study thyroid size
and function in Egyptian patients with common chronic liver
di:-cases.